Effects of early malnutrition and nutritional rehabilitation in rats

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[Effects of early malnutrition and nutritional rehabilitation in rats]

OBJECTIVE: To verify the effects of malnutrition and nutritional rehabilitation regarding seizure threshold, body weight and brain weight in rats. METHODS: Pregnant Wistar rats and their pups were used. Part of the rat pups were submitted to a malnutrition protocol and the rest served as nourished controls. At P15, malnourished and control rats were submitted to status epilepticus induced by fl...

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Effects of maternal malnutrition and postnatal nutritional rehabilitation on brain fatty acids, learning, and memory.

Undernutrition still affects mothers and children in developing countries and thus remains the major focus of nutritional intervention efforts. Neuronal development, which classically includes neurogenesis, migration, maturation, and synapse refinement, begins in utero and continues into the early postnatal period. These processes are not only genetically regulated but also clearly susceptible ...

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ژورنال

عنوان ژورنال: Jornal de Pediatria

سال: 2002

ISSN: 0021-7557

DOI: 10.2223/jped.671